Where to Find Otto's Lab Journal #2 Location - Spider-Man PS4
Video Game Reviews - Spider-Man for PS4 - The Pop Insider
Strong Connections - Marvel's Spider-Man Wiki Guide - IGN
In Marvel's Spider-Man (2018), Otto mentions Dr. Karla Sofen in his lab notes. In the comics, Karla Sofen is the supervillain Moonstone, an enemy of Captain Marvel. : r/GamingDetails